Enter the documented antibiotic allergy — beta-lactam or non-beta-lactam — to see which
antibiotics are likely safe versus those to avoid until allergist evaluation.
Add one or more — pick a drug and it's added to the list; you can keep adding.
Tip: with several allergies listed, click a chip to view that drug's cross-reactivity on its own.
Decision support only — for licensed clinicians. Not a substitute for clinical judgment, specialist
consultation, or pharmacy verification. Beta-lactam cross-reactivity uses a side-chain model based on the 2022
Drug Allergy Practice Parameter. Non-beta-lactam
cross-reactivity is modeled as within-class only.
Adapted from Khan DA et al., Drug allergy: A 2022 practice
parameter update, J Allergy Clin Immunol 2022;150(6):1333–1393; and Broyles AD et al., Practical
Guidance for the Evaluation and Management of Drug Hypersensitivity: Specific Drugs, J Allergy Clin Immunol
Pract 2020;8(9S):S16–S116. No patient data is
entered or stored.